{"id":10182,"date":"2026-10-01T09:58:08","date_gmt":"2026-10-01T08:58:08","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=10182"},"modified":"2026-10-01T09:58:09","modified_gmt":"2026-10-01T08:58:09","slug":"investigating-the-course-of-atopic-eczema-up-to-1-year-following-completion-of-narrowband-ultraviolet-b-phototherapy-2026","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2026\/10\/01\/investigating-the-course-of-atopic-eczema-up-to-1-year-following-completion-of-narrowband-ultraviolet-b-phototherapy-2026\/","title":{"rendered":"Investigating the course of atopic eczema up to 1 year following completion of narrowband ultraviolet B phototherapy (2026)"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Type of publication:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Journal article<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Author(s):<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bajaj, Sonali; Desai, Prachi; Singh, Akansha; *Jain, Dimple; Wahie, Shyamal.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Citation:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Clinical &amp; Experimental Dermatology. 51(8):1412-1418, 2026 Jul 24.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BACKGROUND: Narrowband (NB)-ultraviolet B (UVB) is a second-line treatment for chronic moderate-to-severe atopic eczema unresponsive to adequate topical therapy, and is known to induce good short-term improvement of eczema severity. However, it is unclear how adult patients fare with their eczema severity long after completion of a course of NB-UVB.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">OBJECTIVES: To investigate the severity of atopic eczema in adults, 1 year following completion of NB-UVB, using validated clinical activity measures.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">METHODS: We undertook a multicentre prospective observational study of adults with moderate-to-severe atopic eczema who were prescribed NB-UVB as part of their standard clinical care. Assessments were made at baseline prior to starting NB-UVB, at the end of NB-UVB and at 4, 8 and 12 months after completion of NB-UVB.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">RESULTS: Eighty participants with moderate-to-severe atopic eczema [mean Objective SCORing Atopic Dermatitis (SCORAD) 39.2 (SD 12.8), Patient-Oriented Eczema Measure (POEM) 18.5 (SD 6.4) and Investigator Global Assessment (IGA) 3.2 (SD 0.5)] underwent NB-UVB therapy. Significant reductions were observed post-treatment: Objective SCORAD decreased to 17.8 (SD 11.4), POEM to 8.2 (SD 6.2) and IGA to 1.7 (SD 1.0) (P &lt; 0.001 achieved for all timepoints). These therapeutic effects were sustained at 4, 8 and 12 months post-treatment (n = 27 at 12 months). Loss to follow-up was attributed to nonattendance exacerbated by the COVID-19 pandemic and patient relocation. Mild adverse events (n = 5), including erythema and eczema flares, were reported, with no serious events.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CONCLUSIONS: These findings indicate that NB-UVB may provide a long-lasting effect for patients who complete a course, helping to diminish their eczema severity to a more manageable level.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>DOI:<\/strong> 10.1093\/ced\/llag066<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Journal article Author(s): Bajaj, Sonali; Desai, Prachi; Singh, Akansha; *Jain, Dimple; Wahie, Shyamal. Citation: Clinical &amp; Experimental Dermatology. 51(8):1412-1418, 2026 Jul 24. Abstract: BACKGROUND: Narrowband (NB)-ultraviolet B (UVB) is a second-line treatment for chronic moderate-to-severe atopic eczema<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2026\/10\/01\/investigating-the-course-of-atopic-eczema-up-to-1-year-following-completion-of-narrowband-ultraviolet-b-phototherapy-2026\/\">Read more <span class=\"screen-reader-text\">Investigating the course of atopic eczema up to 1 year following completion of narrowband ultraviolet B phototherapy (2026)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1001],"tags":[1106,286],"class_list":["post-10182","post","type-post","status-publish","format-standard","hentry","category-open-access","tag-1106","tag-dermatology"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/10182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=10182"}],"version-history":[{"count":1,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/10182\/revisions"}],"predecessor-version":[{"id":10183,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/10182\/revisions\/10183"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=10182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=10182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=10182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}