{"id":4370,"date":"2017-02-28T12:20:58","date_gmt":"2017-02-28T12:20:58","guid":{"rendered":"http:\/\/www.library.sath.nhs.uk\/research\/?p=4370"},"modified":"2017-02-28T12:20:58","modified_gmt":"2017-02-28T12:20:58","slug":"incidence-of-postoperative-nausea-and-vomiting-following-gynecological-laparoscopy-a-comparison-of-standard-anesthetic-technique-and-propofol-infusion-2016","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2017\/02\/28\/incidence-of-postoperative-nausea-and-vomiting-following-gynecological-laparoscopy-a-comparison-of-standard-anesthetic-technique-and-propofol-infusion-2016\/","title":{"rendered":"Incidence of postoperative nausea and vomiting following gynecological laparoscopy: A comparison of standard anesthetic technique and propofol infusion (2016)"},"content":{"rendered":"<p><strong>Type of publication:<\/strong><br \/>\nJournal article<\/p>\n<p><strong>Author(s):<\/strong><br \/>\nBhakta P., Ghosh B.R., Singh U., Govind P.S., Gupta A., Kapoor K.S., *Jain R.K., Nag T., Mitra D., Ray M., Singh V., Mukherjee G.<\/p>\n<p><strong>Citation:<\/strong><br \/>\nActa Anaesthesiologica Taiwanica, March 2016(no pagination)<\/p>\n<p><strong>Abstract:<\/strong><br \/>\nObjective: To determine the safety, efficacy, and feasibility of propofol-based anesthesia in gynecological laparoscopies in reducing incidences of postoperative nausea and vomiting compared to a standard anesthesia using thiopentone\/isoflurane. Design: Randomized single-blind (for anesthesia techniques used) and double-blind (for postoperative assessment) controlled trial. Setting: Operation theater, postanesthesia recovery room, teaching hospital. Patients: Sixty ASA (American Society of Anesthesiologists) I and II female patients (aged 20-60 years) scheduled for gynecological laparoscopy were included in the study. Interventions: Patients in Group A received standard anesthesia with thiopentone for induction and maintenance with isoflurane-fentanyl, and those in Group B received propofol for induction and maintenance along with fentanyl. All patients received nitrous oxide, vecuronium, and neostigmine\/glycopyrrolate. No patient received elective preemptive antiemetic, but patients did receive it after more than one episode of vomiting. Measurements: Assessment for incidence of postoperative nausea and vomiting as well as other recovery parameters were carried out over a period of 24 hours. Main Results: Six patients (20%) in Group A and seven patients (23.3%) in Group B experienced nausea. Two patients (6.66%) in Group B had vomiting versus 12 (40%) in Group A (p . &lt;. 0.05). Overall, the incidence of emesis was 60% and 30% in Groups A and B, respectively (p . &lt;. 0.05). All patients in Group B had significantly faster recovery compared with those in Group A. No patient had any overt cardiorespiratory complications. Conclusion: Propofol-based anesthesia was associated with significantly less postoperative vomiting and faster recovery compared to standard anesthesia in patients undergoing gynecological laparoscopy.<\/p>\n<p><strong>Link to full-text: <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1875459716300145\/pdfft?md5=23ae5cc15830c8a727672ad3ea135958&amp;pid=1-s2.0-S1875459716300145-main.pdf\" target=\"_blank\">http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1875459716300145\/pdfft?md5=23ae5cc15830c8a727672ad3ea135958&amp;pid=1-s2.0-S1875459716300145-main.pdf<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Journal article Author(s): Bhakta P., Ghosh B.R., Singh U., Govind P.S., Gupta A., Kapoor K.S., *Jain R.K., Nag T., Mitra D., Ray M., Singh V., Mukherjee G. Citation: Acta Anaesthesiologica Taiwanica, March 2016(no pagination) Abstract: Objective: To<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2017\/02\/28\/incidence-of-postoperative-nausea-and-vomiting-following-gynecological-laparoscopy-a-comparison-of-standard-anesthetic-technique-and-propofol-infusion-2016\/\">Read more <span class=\"screen-reader-text\">Incidence of postoperative nausea and vomiting following gynecological laparoscopy: A comparison of standard anesthetic technique and propofol infusion (2016)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[574,676,480],"class_list":["post-4370","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-574","tag-nausea","tag-postoperative-care"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/4370","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=4370"}],"version-history":[{"count":1,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/4370\/revisions"}],"predecessor-version":[{"id":4373,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/4370\/revisions\/4373"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=4370"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=4370"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=4370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}