{"id":4498,"date":"2017-08-11T08:37:51","date_gmt":"2017-08-11T08:37:51","guid":{"rendered":"http:\/\/www.library.sath.nhs.uk\/research\/?p=4498"},"modified":"2017-12-06T15:16:25","modified_gmt":"2017-12-06T15:16:25","slug":"partial-breast-radiotherapy-after-breast-conservation-surgery-for-patients-with-early-breast-cancer-uk-import-low-trial-5-year-results-from-a-multicentre-randomised-controlled-phase-3-non-infer","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2017\/08\/11\/partial-breast-radiotherapy-after-breast-conservation-surgery-for-patients-with-early-breast-cancer-uk-import-low-trial-5-year-results-from-a-multicentre-randomised-controlled-phase-3-non-infer\/","title":{"rendered":"Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial (2017)"},"content":{"rendered":"<p><strong>Type of publication:<\/strong><br \/>\nRandomised controlled trial<\/p>\n<p><strong>Author(s):<\/strong><br \/>\nCharlotte E Coles, Clare L Griffin, Anna M Kirby, Jenny Titley, *Rajiv K Agrawal, Abdulla Alhasso, Indrani S Bhattacharya, Adrian M Brunt, Laura Ciurlionis, Charlie Chan, Ellen M Donovan, Marie A Emson, Adrian N Harnett, Joanne S Haviland, Penelope Hopwood, Monica L Jefford, Ronald Kaggwa, Elinor J Sawyer, Isabel Syndikus, Yat M Tsang, Duncan A Wheatley, Maggie Wilcox, John R Yarnold, Judith M Bliss, on behalf of the IMPORT Trialists<\/p>\n<p><strong>Citation:<\/strong><br \/>\nLancet, Sep 2017; vol. 390 (no. 10099); p. 1048-1060<\/p>\n<p><strong>Abstract:<\/strong><br \/>\nLocal cancer relapse risk after breast conservation surgery followed by radiotherapy has fallen sharply in many countries, and is influenced by patient age and clinicopathological factors. We hypothesise that partial-breast radiotherapy restricted to the vicinity of the original tumour in women at lower than average risk of local relapse will improve the balance of beneficial versus adverse effects compared with whole-breast radiotherapy.<\/p>\n<p><strong><a href=\"http:\/\/www.thelancet.com\/pdfs\/journals\/lancet\/PIIS0140-6736(17)31145-5.pdf\" target=\"_blank\" rel=\"noopener\">Link to full-text<\/a>\u00a0<\/strong>[Open access]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Randomised controlled trial Author(s): Charlotte E Coles, Clare L Griffin, Anna M Kirby, Jenny Titley, *Rajiv K Agrawal, Abdulla Alhasso, Indrani S Bhattacharya, Adrian M Brunt, Laura Ciurlionis, Charlie Chan, Ellen M Donovan, Marie A Emson, Adrian<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2017\/08\/11\/partial-breast-radiotherapy-after-breast-conservation-surgery-for-patients-with-early-breast-cancer-uk-import-low-trial-5-year-results-from-a-multicentre-randomised-controlled-phase-3-non-infer\/\">Read more <span class=\"screen-reader-text\">Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial (2017)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[677,245],"class_list":["post-4498","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-677","tag-breast-cancer"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/4498","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=4498"}],"version-history":[{"count":2,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/4498\/revisions"}],"predecessor-version":[{"id":4678,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/4498\/revisions\/4678"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=4498"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=4498"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=4498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}