{"id":5920,"date":"2020-05-01T09:13:09","date_gmt":"2020-05-01T08:13:09","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=5920"},"modified":"2021-03-22T09:56:48","modified_gmt":"2021-03-22T09:56:48","slug":"elevated-bmi-significantly-increases-recurrence-rate-of-breast-cancer-a-district-general-hospital-experience-2019","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2020\/05\/01\/elevated-bmi-significantly-increases-recurrence-rate-of-breast-cancer-a-district-general-hospital-experience-2019\/","title":{"rendered":"Elevated BMI Significantly increases recurrence rate of Breast Cancer; a district general hospital experience (2019)"},"content":{"rendered":"<p><strong>Type of publication:<\/strong><br \/>\nPoster presentation<\/p>\n<p><strong>Author(s):<\/strong><br \/>\n*Blossom Lake, *Albert Mansoor, *Donna Appleton<\/p>\n<p><strong>Citation:<\/strong><br \/>\nBritish Journal Surgery; September 2019; Vol 106(S5), p.20 (Poster presentation at Association of Surgeons of Great Britain May 2019)<\/p>\n<p><strong>Abstract:<\/strong><br \/>\nAims: Excess body weight has been shown to be a risk factor for breast cancer recurrence. The aim of this study was to evaluate the effect of BMI on recurrence rate of Breast cancer in Shropshire.<br \/>\nMethods: Retrospective analysis of Somerset Database of all new breast cancers diagnosed from January 2012 to December 2012 at the Shrewsbury &amp; Telford NHS Trust. Clinical portal and pre-op database were used to obtain patient demographics including BMI and recurrence rate. Excluded patients from analysis: no surgery performed, or operated at another hospital. Overall recurrence rate, local recurrence, distant metastasis rate and 5 year disease free survival (DFS) were compared for 3 groups: BMI&lt; 25, overweight; 25.1-29.9,and obese; &gt;30.<br \/>\nResults: 498 new breast cancers were diagnosed in 2012, of these 132 were excluded as per criteria. 366 records were analysed; 40 patients had recurrent breast cancer 10.9%. 97.5% of recurrent patients had one or more prognostic factor, size&gt; 3cm, node positive or Grade 3, with no significant difference between BMI groups for adverse prognostic factors. Overall Recurrence rate for BMI &lt;25 was 5.9%, this was significantly higher in BMI&gt; 25, 13.3% p&lt;0.05.BMI Overall Recurrence rate Local recurrence Distant Metastasis rate 5 year DFS&lt;25 5.9% 0.8% 5.9% 94.1% Overweight 14.4% 4.2% 10.2% 85.6% Obese 12.3% 2.3% 11.5% 87.7%<br \/>\nConclusion: Our experience suggests a significant increase in Breast Cancer recurrence with increasing BMI. Further studies are needed to clarify this and whether methods of reducing BMI may improve disease free survival<\/p>\n<p><a href=\"https:\/\/bjssjournals.onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/bjs.11340\">Link to full-text<\/a> [no password required]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Poster presentation Author(s): *Blossom Lake, *Albert Mansoor, *Donna Appleton Citation: British Journal Surgery; September 2019; Vol 106(S5), p.20 (Poster presentation at Association of Surgeons of Great Britain May 2019) Abstract: Aims: Excess body weight has been shown<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2020\/05\/01\/elevated-bmi-significantly-increases-recurrence-rate-of-breast-cancer-a-district-general-hospital-experience-2019\/\">Read more <span class=\"screen-reader-text\">Elevated BMI Significantly increases recurrence rate of Breast Cancer; a district general hospital experience (2019)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[832,928,245,297,353],"class_list":["post-5920","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-832","tag-bmi","tag-breast-cancer","tag-obesity","tag-oncology"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/5920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=5920"}],"version-history":[{"count":1,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/5920\/revisions"}],"predecessor-version":[{"id":5921,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/5920\/revisions\/5921"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=5920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=5920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=5920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}