{"id":6162,"date":"2020-08-04T08:38:59","date_gmt":"2020-08-04T07:38:59","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=6162"},"modified":"2021-07-01T08:37:57","modified_gmt":"2021-07-01T07:37:57","slug":"prospective-validation-of-the-rapid-clinical-risk-prediction-score-in-adult-patients-with-pleural-infection-the-pilot-study-2020","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2020\/08\/04\/prospective-validation-of-the-rapid-clinical-risk-prediction-score-in-adult-patients-with-pleural-infection-the-pilot-study-2020\/","title":{"rendered":"Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study (2020)"},"content":{"rendered":"

Type of publication:<\/strong>
\nJournal article<\/p>\n

Author(s):<\/strong>
\nCorcoran J.P.; Psallidas I.; Hassan M.; Hallifax R.J.; Rahman N.M.; Dobson M.; Shaw R.; Hedley E.L.; Sabia A.; Robinson B.; Gerry S.; Collins G.S.; Piccolo F.; Popowicz N.D.; Koegelenberg C.F.; Saba T.; Saba J.; Daneshvar C.; Ward N.R.; Fairbairn I.; *Heinink R.; West A.; Stanton A.E.; Holme J.; Kastelik J.A.; Steer H.; Downer N.J.; Haris M.; Baker E.H.; Everett C.F.; Pepperell J.; Bewick T.; Yarmus L.; Maldonado F.; Khan B.; Hart-Thomas A.; Hands G.; Warwick G.; De Fonseka D.; Maskell N.A.; Munavvar M.; Guhan A.; Shahidi M.; Pogson Z.; Dowson L.; Davies H.E.; Yu L.-M.; Miller R.F.<\/p>\n

Citation:<\/strong>
\nThe European respiratory journal; 2020 Nov;56(5)<\/p>\n

Abstract:<\/strong>
\nBACKGROUND: Over 30% of adult patients with pleural infection either die and\/or require surgery. There is no robust means of predicting at baseline presentation which patients will suffer a poor clinical outcome. A validated risk prediction score would allow early identification of high-risk patients, potentially directing more aggressive treatment thereafter. OBJECTIVE(S): To prospectively assess a previously described risk score (RAPID \u2013 Renal (urea), Age, fluid Purulence, Infection source, Dietary (albumin)) in adults with pleural infection. METHOD(S): Prospective observational cohort study recruiting patients undergoing treatment for pleural infection. RAPID score and risk category were calculated at baseline presentation. The primary outcome was mortality at 3 months; secondary outcomes were mortality at 12 months, length of hospital stay, need for thoracic surgery, failure of medical treatment, and lung function at 3 months. RESULT(S): Mortality data were available in 542 of 546 (99.3%) patients recruited. Overall mortality was 10% (54\/542) at 3 months and 19% (102\/542) at 12 months. The RAPID risk category predicted mortality at 3 months; low-risk (RAPID score 0-2) mortality 5\/222 (2.3%, 95%CI 0.9 to 5.7), medium-risk (RAPID score 3-4) mortality 21\/228 (9.2%, 95%CI 6.0 to 13.7), and high-risk (RAPID score 5-7) mortality 27\/92 (29.3%, 95%CI 21.0 to 39.2). C-statistics for the score at 3 and 12 months were 0.78 (95%CI 0.71 to 0.83) and 0.77 (95%CI 0.72 to 0.82) respectively. CONCLUSION(S): The RAPID score stratifies adults with pleural infection according to increasing risk of mortality and should inform future research directed at improving outcomes in this patient population.<\/p>\n","protected":false},"excerpt":{"rendered":"

Type of publication: Journal article Author(s): Corcoran J.P.; Psallidas I.; Hassan M.; Hallifax R.J.; Rahman N.M.; Dobson M.; Shaw R.; Hedley E.L.; Sabia A.; Robinson B.; Gerry S.; Collins G.S.; Piccolo F.; Popowicz N.D.; Koegelenberg C.F.; Saba T.; Saba J.;…<\/span><\/p>\n

Read more Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study (2020)<\/span> ›<\/span><\/a><\/div>\n

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