{"id":7032,"date":"2022-07-19T09:59:13","date_gmt":"2022-07-19T08:59:13","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=7032"},"modified":"2022-07-19T09:59:13","modified_gmt":"2022-07-19T08:59:13","slug":"blood-lactate-level-in-patients-with-severe-covid-19-does-it-have-any-added-value-2021","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2022\/07\/19\/blood-lactate-level-in-patients-with-severe-covid-19-does-it-have-any-added-value-2021\/","title":{"rendered":"Blood lactate level in patients with severe COVID-19: Does it have any added value? (2021)"},"content":{"rendered":"<p><strong>Type of publication:<\/strong><br aria-hidden=\"true\" \/>Conference abstract<\/p>\n<p><strong>Author(s):<\/strong><br aria-hidden=\"true\" \/>*Hassan R.; *Moudgil H.; *Crawford E.J.; *Makan A.; *Srinivasan S.; *Ahmad N.<\/p>\n<p><strong>Citation:<\/strong><br aria-hidden=\"true\" \/>European Respiratory Journal 2021; 58: Suppl. 65, PA3472.<\/p>\n<p><strong>Abstract:<\/strong><br aria-hidden=\"true\" \/>Background: Increased blood lactate (BLac) concentration is common in critically ill patients. They are measured to estimate disease severity, predict morbidity and mortality. A level &gt;2mmol\/L is an outcome predictor in Septicaemia. COVID-19 mimics features of Sepsis with reports suggesting that BLac would be of added benefit in predicting survivorship in patients with COVID-19.<br \/>\nAims: We set out to validate the role of BLac levels in our cohort of RT-PCR+ severe COVID-19 patients admitted to the respiratory support unit (RSU) of a district general hospital in United Kingdom (UK)<br \/>\nMethods: We carried out a retrospective analysis of all patients admitted to the RSU with features of severe COVID-19 as set out by the World Health Organisation (5). Data was collected for the 2 months of November and December 2020. We used Microsoft Excel for analysis and vassar stats for statistical evaluation<br \/>\nResults: 60 patients were admitted to RSU in the time period. 60% males (n=36) with a Mean age (SD) 69.5 (13.6) years<br \/>\nMean (SD) BLac measured in all patients was 1.5 (0.42) mmol\/L. 17% (n=10) patients had BLac between 2 mmol\/L to 2.5 mmol\/L, of which 2 patients have died. Blac level in patients with Age&gt;65 years (n=38) was &lt; 2.0 mmol\/L; Mean (SD) 1.49 mmol\/L (0.42). Overall, 9 patients died during this period with Mean (SD) BLac of survivors 1.51 mmol\/L (0.4) v non-survivors 1.47 mmol\/L (0.54) (p=0.4)<br \/>\nConclusion: Analysis of our small cohort of severe COVID-19 patients\u2019 show<br \/>\n1) Despite having features of Sepsis, Blac is below the critical threshold of 2mmol\/L for majority of the patients<br \/>\n2) Blac &gt;2mmol\/L did not predict increased mortality and there was no significant difference in the Mean Blac between survivors and non survivors<\/p>\n<p><a href=\"https:\/\/erj.ersjournals.com\/content\/58\/suppl_65\/PA3472\">Link to full-text<\/a> [no password required]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication:Conference abstract Author(s):*Hassan R.; *Moudgil H.; *Crawford E.J.; *Makan A.; *Srinivasan S.; *Ahmad N. Citation:European Respiratory Journal 2021; 58: Suppl. 65, PA3472. Abstract:Background: Increased blood lactate (BLac) concentration is common in critically ill patients. They are measured to<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2022\/07\/19\/blood-lactate-level-in-patients-with-severe-covid-19-does-it-have-any-added-value-2021\/\">Read more <span class=\"screen-reader-text\">Blood lactate level in patients with severe COVID-19: Does it have any added value? (2021)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[979,946],"class_list":["post-7032","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-979","tag-covid-19"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/7032","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=7032"}],"version-history":[{"count":1,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/7032\/revisions"}],"predecessor-version":[{"id":7033,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/7032\/revisions\/7033"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=7032"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=7032"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=7032"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}