{"id":7385,"date":"2023-06-08T09:32:40","date_gmt":"2023-06-08T08:32:40","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=7385"},"modified":"2025-11-25T10:13:24","modified_gmt":"2025-11-25T10:13:24","slug":"primary-acinic-cell-carcinoma-in-an-adolescent-female-2023","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2023\/06\/08\/primary-acinic-cell-carcinoma-in-an-adolescent-female-2023\/","title":{"rendered":"Primary acinic cell carcinoma in an adolescent female (2023)"},"content":{"rendered":"<p><strong>Type of publication:<\/strong><br \/>\nJournal article<\/p>\n<p><strong>Author(s):<\/strong><br \/>\nVenkatasami M.; Harrison K.<\/p>\n<p><strong>Citation:<\/strong><br \/>\nAdvances in Oral and Maxillofacial Surgery; Volume 10,\u00a0June 2023, 100419<\/p>\n<p><strong>Abstract:<\/strong><br \/>\nAcinic cell carcinoma (ACC) is a rare, low-grade tumour, accounting for about 17% of all primary salivary gland malignancies in adults. ACC most commonly affects the parotid gland, predominating fifth and sixth decades of life and a female predilection. In the paediatric population, mucoepidermoid carcinoma is the most common parotid malignancy, followed by ACC. We report a case of a 16-year-old female, presenting with a slow-growing right parotid lump. Clinical examination revealed a small right parotid nodule, grade I House-Brackmann score and cervical lymphadenopathy. Radiological investigations revealed a well-circumscribed lobulated lesion in the anterior right parotid gland and reactive lymph nodes. Surgical management included a right partial parotidectomy. Immunohistochemistry was negative for S100, positive with DOG-1 and widespread PAS-D-resistant granules throughout the tumour cells, confirming a diagnosis of ACC. ACC is an important differential diagnosis to consider in salivary gland pathology in the female adolescent patient.<\/p>\n<p><a href=\"https:\/\/libkey.io\/libraries\/1791\/articles\/562853191\/full-text-file\">Link to full-text<\/a> [open access - no password required]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Journal article Author(s): Venkatasami M.; Harrison K. Citation: Advances in Oral and Maxillofacial Surgery; Volume 10,\u00a0June 2023, 100419 Abstract: Acinic cell carcinoma (ACC) is a rare, low-grade tumour, accounting for about 17% of all primary salivary gland<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2023\/06\/08\/primary-acinic-cell-carcinoma-in-an-adolescent-female-2023\/\">Read more <span class=\"screen-reader-text\">Primary acinic cell carcinoma in an adolescent female (2023)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[1001,200],"tags":[1029,1002,429,759,906],"class_list":["post-7385","post","type-post","status-publish","format-standard","hentry","category-open-access","category-staff-publication","tag-1029","tag-gold-open-access","tag-head-and-neck","tag-head-and-neck-cancer","tag-oral-and-maxillofacial-surgery"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/7385","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=7385"}],"version-history":[{"count":3,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/7385\/revisions"}],"predecessor-version":[{"id":9450,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/7385\/revisions\/9450"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=7385"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=7385"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=7385"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}