{"id":8061,"date":"2024-05-16T09:26:37","date_gmt":"2024-05-16T08:26:37","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=8061"},"modified":"2025-02-24T10:22:22","modified_gmt":"2025-02-24T10:22:22","slug":"testing-for-t38-in-myc-bcl6-re-arranged-large-b-cell-lymphoma-identifies-a-high-risk-subgroup-with-inferior-survival-2024","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2024\/05\/16\/testing-for-t38-in-myc-bcl6-re-arranged-large-b-cell-lymphoma-identifies-a-high-risk-subgroup-with-inferior-survival-2024\/","title":{"rendered":"Testing for t(3;8) in MYC\/BCL6 re-arranged large B cell lymphoma identifies a high risk subgroup with inferior survival (2024)"},"content":{"rendered":"\n<p><strong>Type of publication:<\/strong><br>Journal article<\/p>\n\n\n\n<p><strong>Author(s):<\/strong><br>Maybury, Bernard Douglas; James, Lisa Jane BSc (Hons); Phillips, Neil; Venkatadasari, Indrani; Qureshi, Iman; Riley, James William Elliot; Talbot, Georgina; Moosai, Shivir; Giles, Hannah Victoria Dr; Chadderton, Nicola Mrs; Dowds, James; Rakesh, Pallav; Crosland, Henry; Haslam, Aidan; *Lane, Sarah; Vega Gonzalez, Monica; Davies, David; *Cherian, George; Shenouda, Amir; Kaudlay Sathyanarayana, Praveen Kumar; Starczynski, Jane; Rudzki, Zbigniew; Chaganti, Sridhar<\/p>\n\n\n\n<p><strong>Citation:<\/strong><br>Blood. 2024 Apr 22.<\/p>\n\n\n\n<p><strong>Abstract:<\/strong><br>A reciprocal t(3;8) BCL6::MYC fusion is common in large B cell lymphoma (LBCL) with MYC and BCL6 disruption. These pseudo-double hit cases are not adverse, whereas t(3;8) negative MYC\/BCL6 lymphoma has an inferior prognosis relative to other MYC-rearranged LBCL.<\/p>\n\n\n\n<p><strong>Altmetrics:<\/strong>\n<div class=\"altmetric-embed\" data-badge-details=\"right\" data-badge-type=\"medium-donut\" data-pmid=\"38648564\" data-hide-no-mentions=\"true\"><\/div>\n<script type='text\/javascript' src='https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js'><\/script><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication:Journal article Author(s):Maybury, Bernard Douglas; James, Lisa Jane BSc (Hons); Phillips, Neil; Venkatadasari, Indrani; Qureshi, Iman; Riley, James William Elliot; Talbot, Georgina; Moosai, Shivir; Giles, Hannah Victoria Dr; Chadderton, Nicola Mrs; Dowds, James; Rakesh, Pallav; Crosland, Henry; Haslam,<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2024\/05\/16\/testing-for-t38-in-myc-bcl6-re-arranged-large-b-cell-lymphoma-identifies-a-high-risk-subgroup-with-inferior-survival-2024\/\">Read more <span class=\"screen-reader-text\">Testing for t(3;8) in MYC\/BCL6 re-arranged large B cell lymphoma identifies a high risk subgroup with inferior survival (2024)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[1050,740],"class_list":["post-8061","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-1050","tag-haematology"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/8061","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=8061"}],"version-history":[{"count":3,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/8061\/revisions"}],"predecessor-version":[{"id":8471,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/8061\/revisions\/8471"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=8061"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=8061"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=8061"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}