{"id":8370,"date":"2024-12-23T09:12:37","date_gmt":"2024-12-23T09:12:37","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=8370"},"modified":"2024-12-23T09:12:38","modified_gmt":"2024-12-23T09:12:38","slug":"ambulatory-management-of-acute-uncomplicated-diverticulitis-ambudiv-study-a-multicentre-propensity-score-matching-study-2024","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2024\/12\/23\/ambulatory-management-of-acute-uncomplicated-diverticulitis-ambudiv-study-a-multicentre-propensity-score-matching-study-2024\/","title":{"rendered":"Ambulatory management of acute uncomplicated diverticulitis (AmbUDiv study): a multicentre, propensity score matching study (2024)"},"content":{"rendered":"\n

Type of publication:<\/strong><\/p>\n\n\n\n

Journal article<\/p>\n\n\n\n

Author(s):<\/strong><\/p>\n\n\n\n

Mohamedahmed, Ali Yasen; Hamid, Mohammed; Issa, Mohamed; Albendary, Mohamed; *Sultana, Emiko; Zaman, Shafquat; Bhandari, Santosh; Sarma, Diwakar; *Ball, William; Thomas, Pradeep; Husain, Najam.<\/p>\n\n\n\n

Citation:<\/strong><\/p>\n\n\n\n

International Journal of Colorectal Disease. 39(1):184, 2024 Nov 18.<\/p>\n\n\n\n

Abstract:<\/strong><\/p>\n\n\n\n

INTRODUCTION: Recent studies have suggested that ambulatory management is feasible for acute uncomplicated diverticulitis (AUD); however, there is still no consensus regarding the most appropriate management settings. This study presents a multi-centre experience of managing patients presenting with AUD, specifically focusing on clinical outcomes and comparing ambulatory treatment with in-patient management.<\/p>\n\n\n\n

METHODS: A retrospective multi-centre study was conducted across four hospitals in the UK and included all adult patients with computed tomography (CT) confirmed (Hinchey grade 1a) acute diverticulitis over a
12-month period (January \u2013 December 2022). Patient medical records were followed up for 1-year post-index episode, and outcomes were compared between those treated through the ambulatory pathway versus inpatient treatment using 1:1 propensity score matching (PSM). All statistical analysis was performed using the R Foundation for Statistical Computing, version 4.4.<\/p>\n\n\n\n

RESULTS: A total of 348 patients with Hinchey 1a acute diverticulitis were included (260 in-patients; 88 ambulatory pathway), of which nearly a third (31.3%) had a recurrent disease. Inpatient management was dominant (74.7%), with a median of 3 days of hospital stay. PSM resulted in 172 patients equally divided between the two care settings. Ambulatory management was associated with a lower readmission rate (P = 0.02 before PSM, P = 0.08 after PSM), comparable surgical (P = 0.57 before PSM, 0% in both groups after PSM) and radiological interventions (P = 0.99 before and after PSM) within one year. In both matched and non-matched groups, a strong association between readmissions and inpatient management was noted in univariate analysis (P = 0.03 before PSM, P = 0.04 after PSM) and multivariate analysis (P = 0.02 before PSM, P = 0.03 after PSM).<\/p>\n\n\n\n

CONCLUSION: Our study supports the safety and efficacy of managing patients with AUD through a well-designed ambulatory care pathway. In particular, hospital re-admission rates are lower and other outcomes are non-inferior to in-patient treatment. This has implications for substantial cost-savings and better utilisation of limited healthcare resources.<\/p>\n\n\n\n

Link to full-text<\/a> (open access - no password required)<\/p>\n","protected":false},"excerpt":{"rendered":"

Type of publication: Journal article Author(s): Mohamedahmed, Ali Yasen; Hamid, Mohammed; Issa, Mohamed; Albendary, Mohamed; *Sultana, Emiko; Zaman, Shafquat; Bhandari, Santosh; Sarma, Diwakar; *Ball, William; Thomas, Pradeep; Husain, Najam. Citation: International Journal of Colorectal Disease. 39(1):184, 2024 Nov 18. Abstract:…<\/span><\/p>\n

Read more Ambulatory management of acute uncomplicated diverticulitis (AmbUDiv study): a multicentre, propensity score matching study (2024)<\/span> ›<\/span><\/a><\/div>\n

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