{"id":8517,"date":"2025-02-28T09:58:50","date_gmt":"2025-02-28T09:58:50","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=8517"},"modified":"2025-06-12T15:49:23","modified_gmt":"2025-06-12T14:49:23","slug":"assessing-spect-ct-for-the-identification-of-cartilage-lesions-in-the-knee-joint-a-systematic-review-2025","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2025\/02\/28\/assessing-spect-ct-for-the-identification-of-cartilage-lesions-in-the-knee-joint-a-systematic-review-2025\/","title":{"rendered":"Assessing SPECT\/CT for the identification of cartilage lesions in the knee joint: A systematic review (2025)"},"content":{"rendered":"\n<p><strong>Type of publication:<\/strong><\/p>\n\n\n\n<p>Systematic review<\/p>\n\n\n\n<p><strong>Author(s):<\/strong><\/p>\n\n\n\n<p>Rix L.; *Tushingham S.; Wright K.; Snow M.;<\/p>\n\n\n\n<p><strong>Citation:<\/strong><\/p>\n\n\n\n<p>Osteoarthritis and Cartilage Open. 7(1) (no pagination), 2025. Article Number: 100577. Date of Publication: 01 Mar 2025.<\/p>\n\n\n\n<p><strong>Abstract:<\/strong><\/p>\n\n\n\n<p>Background: Single-photon emission computerised tomography with conventional computer tomography (SPECT\/CT) is an emerging technology which may hold clinical value for the identification of cartilage lesions in the knee joint. The intensity and distribution of SPECT\/CT uptake tracer may identify physiological and structural information in the absence of structural change on other imaging modalities.<\/p>\n\n\n\n<p>Objective(s): To systematically assess the utility of SPECT\/CT in the detection of chondral lesions within the knee joint, in patients presenting with knee pain, with or without structural change.<\/p>\n\n\n\n<p>Result(s): PubMed, Science Direct, Web of Knowledge, and NHS databases were searched for English language articles focusing on the diagnostic value of SPECT\/CT for knee chondral lesions and knee pain. Animal studies, cadaver studies, comparator radiological technique other than SPECT\/CT or patients with a pathology other than knee chondral lesions were excluded. From the search, 11,982 manuscripts were identified, and screened for relevance. Seven studies were identified and scored low on QUADAS-2 bias review. SPECT\/CT correlated with lesions found on other imaging modalities and during intraoperative assessment. Furthermore, in some cases, SPECT\/CT out-performed other modalities in the detection of cartilage lesions.<\/p>\n\n\n\n<p>Conclusion(s): Evidence suggests SPECT\/CT may be a useful tool for the detection and localisation of cartilage lesions, particularly in discrepant cases when there is an absence of lesions on other imaging modalities, or a lack of correlation with patients' symptoms. Further studies are required to confirm the conclusions of this review.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2665913125000135\" target=\"_blank\" rel=\"noreferrer noopener\">Link to full-text<\/a> [open access - no password required]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Systematic review Author(s): Rix L.; *Tushingham S.; Wright K.; Snow M.; Citation: Osteoarthritis and Cartilage Open. 7(1) (no pagination), 2025. Article Number: 100577. Date of Publication: 01 Mar 2025. Abstract: Background: Single-photon emission computerised tomography with conventional<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2025\/02\/28\/assessing-spect-ct-for-the-identification-of-cartilage-lesions-in-the-knee-joint-a-systematic-review-2025\/\">Read more <span class=\"screen-reader-text\">Assessing SPECT\/CT for the identification of cartilage lesions in the knee joint: A systematic review (2025)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[1001,200],"tags":[1085,1002,934,994],"class_list":["post-8517","post","type-post","status-publish","format-standard","hentry","category-open-access","category-staff-publication","tag-1085","tag-gold-open-access","tag-knee","tag-trauma-and-orthopaedics"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/8517","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=8517"}],"version-history":[{"count":2,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/8517\/revisions"}],"predecessor-version":[{"id":8709,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/8517\/revisions\/8709"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=8517"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=8517"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=8517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}