{"id":9581,"date":"2025-12-23T08:42:13","date_gmt":"2025-12-23T08:42:13","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=9581"},"modified":"2025-12-23T08:42:14","modified_gmt":"2025-12-23T08:42:14","slug":"two-decades-two-destinies-when-chronic-obstructive-pulmonary-disease-hearts-beat-differently-the-divergent-mortality-trajectories-of-atrial-fibrillation-vs-other-arrhythmias-2025","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2025\/12\/23\/two-decades-two-destinies-when-chronic-obstructive-pulmonary-disease-hearts-beat-differently-the-divergent-mortality-trajectories-of-atrial-fibrillation-vs-other-arrhythmias-2025\/","title":{"rendered":"Two decades, two destinies: When chronic obstructive pulmonary disease hearts beat differently - The divergent mortality trajectories of atrial fibrillation vs other arrhythmias (2025)"},"content":{"rendered":"\n<p><strong>Type of publication:<\/strong><\/p>\n\n\n\n<p>Conference abstract<\/p>\n\n\n\n<p><strong>Author(s):<\/strong><\/p>\n\n\n\n<p>Sarfraz M.R.; Hemida M.F.; *Ali A.; Ishtiaq S.; Patel K.; Hussein M.; Tabasum P.; Basit Kayani A.; Mehmood H.; Mushtaq I.; Rehman S.;<\/p>\n\n\n\n<p><strong>Citation:<\/strong><\/p>\n\n\n\n<p>Thorax. Conference: British Thoracic Society Winter Meeting 2025. Westminster . 80(Supplement 2) (pp A71-A73), 2025. Date of Publication: 01 Nov 2025.<\/p>\n\n\n\n<p><strong>Abstract:<\/strong><\/p>\n\n\n\n<p>Background While arrhythmias are recognized as potential causes of death in chronic obstructive pulmonary disease (COPD) patients. However, temporal trends in arrhythmia-related mortality among COPD patients remain unexamined. Therefore, we conducted a comparative study evaluating mortality trends between atrial fibrillation (AF) and other arrhythmias in COPD patients. Methods A retrospective analysis of was conducted from 1999-2023, using the CDC WONDER database comparing COPD patients with AF (ICD-10: I48) versus other arrhythmias (ICD-10: I47, I49). Age-adjusted mortality rates (AAMRs) per 100,000 population were stratified by demographic variables for adults &gt;=25 years. Joinpoint regression estimated average annual percent changes (AAPC) in mortality trends. Results From 1999-2023, 537,088 COPD-AF deaths were recorded (280,378 Men; 256,710 Women). AAMRs increased significantly from 5.55 to 13.66 (AAPC: +3.87%). Conversely, 168,770 COPD patients with other arrhythmias died (96,472 Men; 72,298 Women), with AAMRs declining significantly from 5.19 to 2.04 (AAPC: -3.56%). Men consistently showed higher mortality rates in both COPD with AF and other arrhythmias. In COPD-AF, AAMRs increased significantly for both genders (p&lt;0.000001): men (7.96 to 16.95; AAPC: +3.23%) and women (4.17 to 11.19; AAPC: +4.18%). Conversely, in the COPD with other arrhythmias cohort, mortality rates decreased significantly (p&lt;0.000001) for both men (AAMR: 7.68 to 2.67; AAPC: -4.05%) and women (AAMR: 3.58 to 1.52; AAPC: -3.16%). Inpatient medical facilities were the most common place of death for both groups, though COPD-AF patients had fewer inpatient deaths (59,284) than those with other arrhythmias (190,982). Both cohorts showed a notable shift toward increased home deaths over the study period. Racially, Whites had the highest AAMRs in both groups (AF: 11.04; other: 3.32), followed by American Indians (AF: 8.18; other: 2.78). Regionally, the Midwest showed highest mortality with opposing trends: upward for AF (AAPC: +4.89%) and downward for other arrhythmias (AAPC: -3.30%) p&lt;0.000001. At state level, Vermont had the highest COPD-AF mortality (AAMR: 16.33), while Ohio had the highest AAMR for other arrhythmias (5.20). Conclusion COPD-AF mortality increased dramatically while other arrhythmia mortality declined significantly. Men showed consistently higher mortality with notable demographic disparities. These opposing trends suggest AF represents an emerging threat requiring targeted interventions.<\/p>\n\n\n\n<p><strong>DOI:&nbsp;<\/strong>10.1136\/thorax-2025-BTSabstracts.104<\/p>\n\n\n\n<p><a href=\"https:\/\/thorax.bmj.com\/content\/80\/Suppl_2\/A71.2\">Link to full-text<\/a> [NHS OpenAthens account required]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Conference abstract Author(s): Sarfraz M.R.; Hemida M.F.; *Ali A.; Ishtiaq S.; Patel K.; Hussein M.; Tabasum P.; Basit Kayani A.; Mehmood H.; Mushtaq I.; Rehman S.; Citation: Thorax. Conference: British Thoracic Society Winter Meeting 2025. Westminster .<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2025\/12\/23\/two-decades-two-destinies-when-chronic-obstructive-pulmonary-disease-hearts-beat-differently-the-divergent-mortality-trajectories-of-atrial-fibrillation-vs-other-arrhythmias-2025\/\">Read more <span class=\"screen-reader-text\">Two decades, two destinies: When chronic obstructive pulmonary disease hearts beat differently - The divergent mortality trajectories of atrial fibrillation vs other arrhythmias (2025)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[1085,997,215],"class_list":["post-9581","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-1085","tag-cardiovascular-care","tag-copd"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/9581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=9581"}],"version-history":[{"count":1,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/9581\/revisions"}],"predecessor-version":[{"id":9582,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/9581\/revisions\/9582"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=9581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=9581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=9581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}