{"id":9643,"date":"2026-01-23T09:32:01","date_gmt":"2026-01-23T09:32:01","guid":{"rendered":"https:\/\/www.library.sath.nhs.uk\/research\/?p=9643"},"modified":"2026-01-23T09:32:01","modified_gmt":"2026-01-23T09:32:01","slug":"a-young-lady-with-diabetic-mastopathy-dmp-a-less-well-known-complication-of-diabetes-2024","status":"publish","type":"post","link":"https:\/\/www.library.sath.nhs.uk\/research\/2026\/01\/23\/a-young-lady-with-diabetic-mastopathy-dmp-a-less-well-known-complication-of-diabetes-2024\/","title":{"rendered":"A young lady with diabetic mastopathy (DMP): A less well-known complication of diabetes (2024)"},"content":{"rendered":"\n<p><strong>Type of publication:<\/strong><\/p>\n\n\n\n<p>Conference abstract<\/p>\n\n\n\n<p><strong>Author(s):<\/strong><\/p>\n\n\n\n<p>*Cane C.L.; *Jones A.M.; *Moulik P.K.<\/p>\n\n\n\n<p><strong>Citation:<\/strong><\/p>\n\n\n\n<p>Diabetic Medicine. Conference: Diabetes UK Professional Conference 2024. London . 41(Supplement 1) (no pagination), 2024. Date of Publication: 01 Apr 2024.<\/p>\n\n\n\n<p><strong>Abstract:<\/strong><\/p>\n\n\n\n<p>A 26-year-old nulliparous female presented with a 2-week history of a right breast lump. She had type 1 diabetes for 17 years and polycystic ovaries. Her diabetes distress led to suboptimal glycaemic control. There was firm tissue under the right nipple-areola complex, and ultrasound (US) demonstrated a suspicious 43-mm mixed echogenic lesion with posterior shadowing (U4). Core biopsy revealed marked fibrosis with fibroblasts and entrapped benign breast ducts and adipose tissue. Breast ducts were highlighted by epithelial markers (AE1\/3 and small P63), blood vessels by CD34, and fibroblasts and myoepithelial layers by smooth muscle actin (SMA). She was reassured; 2 years later she developed a left breast lump and 26-mm focal hypoechoic glandular lesion on US, right breast lesion unchanged. A diagnosis of DMP was made. DMP occurs in 20- to 40 year-old women with long duration of type 1 diabetes. It can occur in men rarely. It presents with a painless, hard, mobile breast lesions which are irregular. Bilateral lesions develop in 50% patients. Axillary lymphadenopathy is absent. Mammography reveals dense glandular tissue and US shows acoustic shadows behind the lesion. Core biopsy is recommended. DMP is a benign condition which may raise concerns of breast cancer. It may be associated with autoimmunity and occasionally seen in insulin treated type 2 diabetes, systemic lupus erythematosus and Hashimoto's. Microscopy shows periductal, perilobular and perivascular B-lymphocytic infiltrates with some T cells, fibroblast proliferation and collagen. Management is conservative unless a larger lesion requires excision. To date, only one case report has been published on breast cancer in a patient with DMP.<\/p>\n\n\n\n<p><strong>DOI:&nbsp;<\/strong>10.1111\/dme.15295<\/p>\n\n\n\n<p><a href=\"https:\/\/libkey.io\/libraries\/1791\/articles\/612692066\/full-text-file\">Link to full-text<\/a> [no password required]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of publication: Conference abstract Author(s): *Cane C.L.; *Jones A.M.; *Moulik P.K. Citation: Diabetic Medicine. Conference: Diabetes UK Professional Conference 2024. London . 41(Supplement 1) (no pagination), 2024. Date of Publication: 01 Apr 2024. Abstract: A 26-year-old nulliparous female presented<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.library.sath.nhs.uk\/research\/2026\/01\/23\/a-young-lady-with-diabetic-mastopathy-dmp-a-less-well-known-complication-of-diabetes-2024\/\">Read more <span class=\"screen-reader-text\">A young lady with diabetic mastopathy (DMP): A less well-known complication of diabetes (2024)<\/span><span class=\"meta-nav\"> &#8250;<\/span><\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[1050,989],"class_list":["post-9643","post","type-post","status-publish","format-standard","hentry","category-staff-publication","tag-1050","tag-endocrinology-and-diabetes"],"_links":{"self":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/9643","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/comments?post=9643"}],"version-history":[{"count":1,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/9643\/revisions"}],"predecessor-version":[{"id":9644,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/posts\/9643\/revisions\/9644"}],"wp:attachment":[{"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/media?parent=9643"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/categories?post=9643"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.library.sath.nhs.uk\/research\/wp-json\/wp\/v2\/tags?post=9643"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}