Postmenopausal bleeding in women taking HRT - Quality improvement project (2024)

Type of publication:

Conference abstract

Author(s):

*Magar C.K.P.; *Radothra A.; Gbenga A.; *Ritchie J.;

Citation:

Post Reproductive Health. Conference: 33rd British Menopause Society Annual Scientific Conference, BMS 2024. Kenilworth United Kingdom. 30(1 Supplement) (pp 33S-34S), 2024. Date of Publication: 01 Sep 2024.

Abstract:

Objective: Since the 'Davina Effect', there has been rise in the demand for HRT, with a significant increase in HRT prescriptions up by 35% compared to 2021/22, as result there has been an increase in patients presenting with Postmenopausal bleeding on HRT attending our one stop hysteroscopy clinic. The aim of this study was to identify the number of cancers in patients presenting with postmenopausal bleeding who are taking HRT attending our one stop hysteroscopy clinic. Method(s): Prospective study with a sample size of 100 cases. Patient selection – Any patient coming to one stop hysteroscopy clinic with Postmenopausal bleeding on HRT. Sample period: 1st January 2023 to end of August 2023. Data was collected from the patient directly in the designed proforma then scanned to the Microsoft Excel. Result(s): 91% were postmenopausal with average age of 50-59 years and 90% of patient were taking continuous combined HRT. 9% were premenopausal on sequential HRT. 61% of women were on HRT for >12 months however 4% were referred within 3 months of HRT and 10% within 3-6 months. Following transvaginal ultrasound scan, 9% of patients were reassured and discharged, 36% underwent endometrial biopsy and 55% underwent hysteroscopy and endometrial biopsy. 2% were diagnosed with endometrial cancer and 89% had normal histology with a benign cause to explained their postmenopausal bleeding. Of the two patients diagnosed with endometrial cancer, one patient had a endometrial thickness (ET) of 4mm and one of 13mm. The patient with an ET of 4mm was also low risk with a normal BMI, and had been on HRT for 6 months. Conclusion(s): Cancer rate detected in our population is 2% which is very similar to the national rate (1-2%). This result highlights the importance of investigating patients with Postmenopausal bleeding on HRT with endometrial thickness of >=4 mm.

DOI: 10.1177/20533691241273937