Type of publication:Journal article
Author(s):Kakroo S.N.; Beg M.A.; *Kakroo B.
Citation:Journal of Pakistan Association of Dermatologists. 31(4) (pp 588-594), 2021
Abstract:Objective We sought to evaluate the efficacy of wet wrap therapy treatment in patients with Atopic dermatitis. Methods Total 30 patients, (25 males and 5 females) were enrolled in this study with severe dermatitis [SCORAD] score >=50) were enrolled in this study. For disease severity SCORAD was used, for quality of life dermatology life quality index (DLQI) scores, visual analog scale (VAS) for pruritus and investigator's global assessment (IGA) was used. For evaluation of water content in the corneum, the capacitance was measured by Corneometer (Courage and Khazaka, Cologne, Germany), and TEWL was measured by Tewameter TM210 (Courage and Khazaka). The lipid amount of skin surface was assessed by Sebumeter (Courage and Khazaka). The patients underwent WWT (daily dose: 15 g Mometasone furoate cream+100g Vaseline ointment) twice daily for 2 h/session for 7 days. Results There was significant improvement in lesions, quality of life and itching. SCORAD was clearly decreased, epidermal water content was increased, and transepidermal water loss was decreased after wet-wrap dressing. Conclusion Wet wrap therapy (WWT) can relieve pruritus, reduce skin lesions, and improve quality of life.
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