The effect of male fetal gender on the cesarean section rate in greek women with induced labor (2019)

Type of publication:
Journal article

Author(s):
Antonakou A.; Souma M.; Tsourlou E.; *Papoutsis D.

Citation:
Archives of Hellenic Medicine; 2019; vol. 36 (no. 5); p. 643-649

Abstract:
OBJECTIVE To explore the effect of fetal gender on the mode of delivery in women with induced labor.
METHOD We collected data retrospectively on women who underwent induction of labor in a tertiary Greek hospital over a one-year period. The maternal demographic characteristics, details of labor and delivery, and neonatal data were retrieved from the medical records. Multiple logistic regression analysis was used to identify whether or not the fetal gender was an independent risk factor for cesarean section (CS). RESULTS The sample consisted of 359 women with a mean age of 30+/-5.4 years. Maternal characteristics were similar in women who delivered male and female babies. The birth weight was significantly greater in male than female babies. A significantly higher CS rate was recorded in women with male babies than in those with female babies (39.4% vs 25.5%). Multiple regression analysis showed that the male fetal gender increased almost two-fold the risk of CS, even after adjusting for birth weight (OR=2.04, 95% CI: 1.11-3.76; p=0.022).
CONCLUSIONS We showed in this study that the male fetal gender is a factor that might affect the mode of delivery in women with induced labor. This gender relationship persisted after adjusting for birth weight, indicating that factors other than birth weight could explain this effect.

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The incidence of and risk factors for complications when removing a single uterine fibroid during cesarean section: a retrospective study with use of two comparison groups (2019)

Type of publication:
Journal article

Author(s):
Sparic R.; Kadija S.; Spremovic Radjenovic S.; Lackovic M.; Bukumiric Z.; *Papoutsis D.; Malvasi A.; Tinelli A.

Citation:
Journal of Maternal-Fetal and Neonatal Medicine; 2019, Jan 30:1-8 [epub ahead of print]

Abstract:
Purpose: To determine the incidence of and risk factors for perioperative complications in women with a single uterine fibroid, who had a cesarean myomectomy (CM). Method(s): This was a retrospective study of women who had a CM between 2015-2016. They were compared versus women who had a cesarean section (CS) alone and nonpregnant women who had a laparotomic myomectomy (LM). Result(s): We identified 44 CM women, 51 CS patients, and 44 LM women. Those with a CM in most cases had subserosal at the anterior uterine wall and near the lower uterine segment (LUS), as most frequent fibroids; moreover, they had, on average, 18 min longer surgery duration versus CS alone. CM did not affect the Apgar scores and the incidence of minor and major complications was 36.4% and 29.5%, with the most frequent being
postoperative anemia (36.4%) and intraoperative hemorrhage (29.5%). No significant differences were reported on both minor and major complications in the three groups. The following variables were found to be significant predictors in univariate logistic regression analysis for the occurrence of major complications in women who had a CM: the fibroid size (OR = 1.040, 95%CI: 1.014-1.066, p =.002), and duration of surgery (OR = 1.059, 5%CI:1.012-1.108, p =.013). The fibroid diameter cut-off was 75.0 mm (sensitivity 69.2%; specificity 90.3%), and the surgery duration was 87.5 min (sensitivity 53.8%; specificity 93.5%). Conclusion(s): CM appears safe, with no additional risks when compared to CS alone and LM in the women of reproductive age.

The SaTH risk-assessment tool for the prediction of emergency cesarean section in women having induction of labor for all indications: a large-cohort based study. (2017)

Type of publication:
Journal article

Author(s):
*Papoutsis, Dimitrios, Antonakou, Angeliki, *Gornall, Adam, Tzavara, Chara, *Mohajer, Michelle

Citation:
Archives of Gynecology and Obstetrics, Jan 2017, vol. 295, no. 1, p. 59-66

Abstract:
To develop a risk-assessment model for the prediction of emergency cesarean section (CS) in women having induction of labor (IOL). This was an observational cohort study of women with IOL for any indication between 2007 and 2013. Women induced for stillbirths and with multiple pregnancies were excluded. The primary objective was to identify risk factors associated with CS delivery and to construct a risk-prediction tool. 6169 women were identified with mean age of 28.9 years. Primiparity involved 47.1 %, CS rate was 13.3 % and post-date pregnancies were 32.4 %. Risk factors for CS were: age >30 years, BMI >25 kg/m2, primiparity, black-ethnicity, non post-date pregnancy, meconium-stained liquor, epidural analgesia, and male fetal gender. Each factor was assigned a score and with increasing scores the CS rate increased. The CS rate was 5.4 % for a score <11, while for a score ≥11 it increased to 25.0 %. The model had a sensitivity, specificity, negative predictive value and positive predictive value of 75.8, 65.1, 93.8 and 25.0 %, respectively. We have constructed a risk-prediction tool for CS delivery in women with IOL. The risk-assessment tool for the prediction of emergency CS in induced labor has a high negative-predictive value and can provide reassurance to presumed low-risk women.